GCH1 (Gene)

Description: GTP cyclohydrolase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GCH1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GCH1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GCH1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GCH1.

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Gene Sets (2112)

LINCS L1000 Chem Pert Consensus Sigs (1090)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (2)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1005)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (10)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
ferulic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	0.03555556
Asiaticoside Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	0.008728006
(-)-Phenyl-carbamic acid 1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-yl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	0.005235316
sulfanitran Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	-0.0430008
LOSARTAN Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	0.0030127892
(5-{3-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]isoxazol-5-yl}-2H-tetrazol-2-yl)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	0.004997661
austricine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	-0.009593961
SA-1939079 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	0.01887141
ichthynone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	-0.009253113
Merbromin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GCH1 Gene (Entity type)	0.020346988