TLE1 (Gene)

Description: TLE family member 1, transcriptional corepressor

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TLE1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TLE1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TLE1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TLE1.

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Gene Sets (572)

LINCS L1000 Chem Pert Consensus Sigs (404)

A gene set library provided by LINCS

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (166)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Promethazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	0.0048235976
givinostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	0.018523814
Ethotoin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	-0.004199772
KFGENEBIN:TLE1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)
Ambrisentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	0.00310897
CHEMBL3360855::EPZ005687::US9175331, 7 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	0.014969338
AMG-9810 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	0.008192669
Chromomycin-a3 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	-0.015940532
beclometasone dipropionate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	0.0073886407
L-glutamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	0.009118399