TPP1 (Gene)

Description: tripeptidyl peptidase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TPP1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TPP1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TPP1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TPP1.

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Gene Sets (890)

LINCS L1000 Chem Pert Consensus Sigs (543)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (8)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (8)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (330)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Pemetrexed Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	-0.0056811287
AZD-1152 HQPA Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	-0.0023780966
Loratadine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	-0.0030627253
(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	0.010065423
(E/Z)-3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	-0.0037103433
latrunculin-b Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	0.010863702
Troglitazone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	-0.0030019195
KFGENEBIN:TPP1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)
ICI-162846 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	-0.004937853
FTI 276 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPP1 Gene (Entity type)	-0.005158296