SHC1 (Gene)

Description: SHC adaptor protein 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SHC1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SHC1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SHC1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SHC1.

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Gene Sets (958)

LINCS L1000 Chem Pert Consensus Sigs (616)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (332)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Medetomidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	0.009474764
propanoic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	0.018106138
methoxypyruvic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	0.018692216
minodronic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	0.0062641287
Gallopamil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	0.009404183
Barasertib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	-0.0056554726
suramin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	-0.017099801
4-(2-(2-(dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	0.006709523
dihydrocapsaicin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	-0.020655518
BG-1002 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SHC1 Gene (Entity type)	-0.024717761