PRSS3 (Gene)

Description: serine protease 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRSS3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRSS3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRSS3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRSS3.

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Gene Sets (1137)

LINCS L1000 Chem Pert Consensus Sigs (620)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (497)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (7)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SB-590885 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	0.0044210474
Geldanamycin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	-0.008626204
SA-1922959 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	-0.0105731
Prostaglandin F2alpha Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	0.005062316
diazepam Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	-0.003187082
Adamantan-1-ylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	-0.0026296787
KFGENEBIN:PRSS3-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)
SA-1456170 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	-0.015617063
(S)-Efavirenz; (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	-0.0038745117
SA-417716 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRSS3 Gene (Entity type)	0.014021904