HSD17B6 (Gene)

Description: hydroxysteroid 17-beta dehydrogenase 6

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HSD17B6's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HSD17B6.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HSD17B6.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HSD17B6.

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Gene Sets (987)

LINCS L1000 Chem Pert Consensus Sigs (532)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (440)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (5)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
HSD17B6 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraen-1-ol Metabolite (Entity type)
HSD17B6 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	all-<i>trans</i>-retinal Metabolite (Entity type)
tolazoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSD17B6 Gene (Entity type)	-0.0069186147
2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSD17B6 Gene (Entity type)	-0.0029550197
HSD17B6 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nicotinamide adenine dinucleotide (NAD) Metabolite (Entity type)
tyloxapol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSD17B6 Gene (Entity type)	-0.017064743
SA-1920683 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSD17B6 Gene (Entity type)	-0.009862796
SA-1462246 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD17B6 Gene (Entity type)	0.013806111
tribenoside Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD17B6 Gene (Entity type)	0.008923268
anecortave-acetate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD17B6 Gene (Entity type)	0.004067983