CTSE (Gene)

Ensembl Gene ID: ENSG00000196188

Entrez Gene ID: 1510

Description: cathepsin E

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CTSE's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CTSE.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CTSE.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CTSE.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CTSE.

Gene Sets (944)

LINCS L1000 Chem Pert Consensus Sigs (513)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (397)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (18)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
sotalol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.003186363
SA-1937516 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.012297732
KW-06 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.015820958
emapunil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.003411315
Sulfadoxine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.0061956616
dipivefrine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.008912785
Demeclocycline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.010000958
leu-enkephalin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.011469847
ICI-89406 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	0.0077099525
imidazolidinyl-urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSE Gene (Entity type)	-0.019561581

sotalol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.003186363

SA-1937516
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.012297732

KW-06
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.015820958

emapunil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.003411315

Sulfadoxine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.0061956616

dipivefrine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.008912785

Demeclocycline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.010000958

leu-enkephalin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.011469847

ICI-89406
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
0.0077099525

imidazolidinyl-urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSE
Gene (Entity type)
-0.019561581

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.