PFAS (Gene)

Entrez Gene ID: 5198

Description: phosphoribosylformylglycinamidine synthase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PFAS's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PFAS.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PFAS.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PFAS.

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Gene Sets (809)

LINCS L1000 Chem Pert Consensus Sigs (170)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (85)

A gene set library provided by LINCS

rummageo gene perturbations (205)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (36)

A gene set library provided by LINCS

rummageo chemical perturbations (307)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	L-glutamine Metabolite (Entity type)
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	glutamic acid Metabolite (Entity type)
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Adenosine Diphosphate Metabolite (Entity type)
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	glutamine Metabolite (Entity type)
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ATP Metabolite (Entity type)
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ADP Metabolite (Entity type)
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	(S)-glutamate Metabolite (Entity type)
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	N(2)-Formyl-N(1)-(5-phospho-D-ribosyl)glycinamide Metabolite (Entity type)
KFGENEBIN:PFAS-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PFAS Gene (Entity type)
PFAS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	atp binding Metabolite (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
L-glutamine
Metabolite (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
glutamic acid
Metabolite (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Adenosine Diphosphate
Metabolite (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
glutamine
Metabolite (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ATP
Metabolite (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ADP
Metabolite (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
(S)-glutamate
Metabolite (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
N(2)-Formyl-N(1)-(5-phospho-D-ribosyl)glycinamide
Metabolite (Entity type)

KFGENEBIN:PFAS-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
PFAS
Gene (Entity type)

PFAS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
atp binding
Metabolite (Entity type)

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.