SPHK1 (Gene)

Entrez Gene ID: 8877

Description: sphingosine kinase 1

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SPHK1's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SPHK1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SPHK1.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SPHK1.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SPHK1.

Gene Sets (1409)

LINCS L1000 Chem Pert Consensus Sigs (236)

A gene set library provided by LINCS

Metabolomics Workbench Metabolites 2022 (4)

A gene set library provided by MW

ARCHS4 IDG Coexp (6)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (7)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (124)

A gene set library provided by LINCS

rummageo gene perturbations (188)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (3)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (336)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (216)

A gene set library provided by LINCS

rummageo chemical perturbations (286)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ATP Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Sphingosine Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	sphingosine Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Adenosine Diphosphate Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	dihydrosphingosine 1-phosphate Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	sphinganine Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	sphingosine 1-phosphate Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ADP Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Sphingosine-1-phosphate Metabolite (Entity type)
SPHK1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	atp binding Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ATP
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Sphingosine
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
sphingosine
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Adenosine Diphosphate
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
dihydrosphingosine 1-phosphate
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
sphinganine
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
sphingosine 1-phosphate
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ADP
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Sphingosine-1-phosphate
Metabolite (Entity type)

SPHK1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
atp binding
Metabolite (Entity type)

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.