ITGAM (Gene)

Entrez Gene ID: 3684

Description: integrin subunit alpha M

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ITGAM's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ITGAM.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ITGAM.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ITGAM.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ITGAM.

Gene Sets (2719)

LINCS L1000 Chem Pert Consensus Sigs (555)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (12)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (12)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (640)

A gene set library provided by LINCS

rummageo gene perturbations (126)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (307)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (911)

A gene set library provided by LINCS

rummageo chemical perturbations (136)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (6)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (7)

A gene set library provided by GTEx

HuBMAP ASCT-B (5)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Entospletinib; 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	-0.005315014
irilin-a Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	-0.009183654
CTB Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	-0.004429745
AZD-5069 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	0.0045030215
KFGENEBIN:ITGAM-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)
asiatic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	0.0078666555
RAN-05 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	-0.009191803
1-(2,6-dimethylphenoxy)propan-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	0.0072289263
GSK-J1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	-0.0037198367
MK2a inhibitor Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITGAM Gene (Entity type)	0.012510781

Entospletinib; 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
-0.005315014

irilin-a
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
-0.009183654

CTB
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
-0.004429745

AZD-5069
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
0.0045030215

KFGENEBIN:ITGAM-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)

asiatic-acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
0.0078666555

RAN-05
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
-0.009191803

1-(2,6-dimethylphenoxy)propan-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
0.0072289263

GSK-J1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
-0.0037198367

MK2a inhibitor
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ITGAM
Gene (Entity type)
0.012510781

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.