PPCS (Gene)

Entrez Gene ID: 79717

Description: phosphopantothenoylcysteine synthetase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PPCS's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PPCS.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PPCS.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PPCS.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PPCS.

Gene Sets (529)

LINCS L1000 Chem Pert Consensus Sigs (16)

A gene set library provided by LINCS

Metabolomics Workbench Metabolites 2022 (3)

A gene set library provided by MW

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (26)

A gene set library provided by LINCS

rummageo gene perturbations (92)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (213)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (3)

A gene set library provided by LINCS

rummageo chemical perturbations (173)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target
PPCS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ATP Metabolite (Entity type)
PPCS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	atp binding Metabolite (Entity type)
PPCS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	cysteine Metabolite (Entity type)
PPCS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	(R)-4'-Phosphopantothenic acid Metabolite (Entity type)
PPCS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	adenosine monophosphate Metabolite (Entity type)
KFGENEBIN:PPCS-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PPCS Gene (Entity type)
PPCS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate Metabolite (Entity type)
PPCS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Cysteine Metabolite (Entity type)

PPCS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ATP
Metabolite (Entity type)

PPCS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
atp binding
Metabolite (Entity type)

PPCS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
cysteine
Metabolite (Entity type)

PPCS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
(R)-4'-Phosphopantothenic acid
Metabolite (Entity type)

PPCS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
adenosine monophosphate
Metabolite (Entity type)

KFGENEBIN:PPCS-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
PPCS
Gene (Entity type)

PPCS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
Metabolite (Entity type)

PPCS
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Cysteine
Metabolite (Entity type)

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.