TNFAIP6 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:7130, HGNC:11898, MIM:600410, NM_007115, NP_009046, TNF alpha induced protein 6, TNFAIP6, TSG-6, TSG6

Omim:OMIM:600410

Id:ENSG00000123610

Hgnc:HGNC:11898

Entrez:7130

Ensembl:ENSG00000123610

Description:TNF alpha induced protein 6

The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TNFAIP6's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TNFAIP6.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TNFAIP6.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TNFAIP6.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TNFAIP6.

Results found

Linked to

	Label	Description
	GSE218097 SOX10 overexpression glial cell 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE238213 dopamine 5 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE226115 GSE226116 doxorubicin cardiac endothelial cell 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE128255 NDP knockdown stem cell 3 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE233679 nicotinamide 6 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE233679 nicotinamide 6 v 10 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE226525 GSE226527 HNRNPH2 knockout 4 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE199204 GSE211619 glutamine 4 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE142210 2 V 5 PANOBINOSTAT HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE108464 AZ-628 1 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE218097 SOX10 overexpression glial cell 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE238213 dopamine 5 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE226115 GSE226116 doxorubicin cardiac endothelial cell 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE128255 NDP knockdown stem cell 3 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE233679 nicotinamide 6 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE233679 nicotinamide 6 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE226525 GSE226527 HNRNPH2 knockout 4 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE199204 GSE211619 glutamine 4 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE142210 2 V 5 PANOBINOSTAT HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE108464 AZ-628 1 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.