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FOXM1 (Gene)

Ensembl Gene ID: ENSG00000111206

Entrez Gene ID: 2305

Description: forkhead box M1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View FOXM1's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with FOXM1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using FOXM1.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for FOXM1.

Gene Sets (1765)

LINCS L1000 Chem Pert Consensus Sigs (292)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (700)

A gene set library provided by LINCS

rummageo gene perturbations (241)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (139)

A gene set library provided by LINCS

rummageo chemical perturbations (386)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Genotype Tissue Expression

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphosphonic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	0.007772756
	1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	0.0040316423
	3-(4-(((2-(1H-indol-3-yl)ethyl)(2-hydroxyethyl)amino)methyl)phenyl)-N-hydroxyacrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	-0.009497625
	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	-0.005456558
	KFGENEBIN:FOXM1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)
	Resminostat; (E)-3-(1-((4-((dimethylamino)methyl)phenyl)sulfonyl)-1H-pyrrol-3-yl)-N-hydroxyacrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	-0.0059625315
	Scriptaid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	-0.0103840055
	Palbociclib; Ibrance Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	-0.016567588
	Nutlin-2 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	-0.0034086523
	Abexinostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOXM1 Gene (Entity type)	-0.011115092

(3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphosphonic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
0.007772756

1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
0.0040316423

3-(4-(((2-(1H-indol-3-yl)ethyl)(2-hydroxyethyl)amino)methyl)phenyl)-N-hydroxyacrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
-0.009497625

2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
-0.005456558

KFGENEBIN:FOXM1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)

Resminostat; (E)-3-(1-((4-((dimethylamino)methyl)phenyl)sulfonyl)-1H-pyrrol-3-yl)-N-hydroxyacrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
-0.0059625315

Scriptaid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
-0.0103840055

Palbociclib; Ibrance
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
-0.016567588

Nutlin-2
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
-0.0034086523

Abexinostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOXM1
Gene (Entity type)
-0.011115092

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.