HERC5 (Gene)

Description: HECT and RLD domain containing E3 ubiquitin protein ligase 5

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HERC5's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HERC5.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HERC5.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HERC5.

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Gene Sets (1870)

LINCS L1000 Chem Pert Consensus Sigs (870)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (7)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (993)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SD-169 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.0142067475
cerdulatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.0078957975
Oxidopamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.011732529
isoreserpine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.01352905
BJM-AF-64 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.0076185926
7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.011362339
SA-1457305 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.009922171
LDN-57444 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	0.010523932
Trifluridine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	0.0071138768
APEC Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HERC5 Gene (Entity type)	-0.014067714