TMPRSS3 (Gene)

Description: transmembrane serine protease 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TMPRSS3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TMPRSS3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TMPRSS3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TMPRSS3.

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Gene Sets (1102)

LINCS L1000 Chem Pert Consensus Sigs (596)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (493)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (10)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
devazepide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	-0.010336327
KFGENEBIN:TMPRSS3-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)
Naftidrofuryl Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	0.0041555953
Bromhexine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	0.007183928
leoidin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	0.009935001
3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	0.016624382
Y-26763 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	-0.003477815
HTS-12264SC Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	0.010985987
lonafarnib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	0.0037731854
caffeine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMPRSS3 Gene (Entity type)	-0.0028627994