PRSS21 (Gene)

Description: serine protease 21

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRSS21's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRSS21.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRSS21.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRSS21.

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Gene Sets (1195)

LINCS L1000 Chem Pert Consensus Sigs (581)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (10)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (595)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (8)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Tetramisole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	0.008631715
14-(S)-2,9-dihydroxyl-3,10-dimethoxytetrahyrdooxyprotoberberine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	0.009499051
Enasidenib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	0.0054688035
KFGENEBIN:PRSS21-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)
iopanoic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	-0.008908663
SID11111783 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	-0.0052823583
ceforanide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	-0.007565806
Darifenacin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	0.0036439884
Mebeverine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	-0.008055796
SA-1921783 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRSS21 Gene (Entity type)	-0.011721538