TYMP (Gene)

Description: thymidine phosphorylase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TYMP's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TYMP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TYMP.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TYMP.

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Gene Sets (1016)

LINCS L1000 Chem Pert Consensus Sigs (464)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (11)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (541)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
TYMP Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Deoxyuridine Metabolite (Entity type)
TYMP Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Deoxyribose 1-phosphate Metabolite (Entity type)
SID11113907 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYMP Gene (Entity type)	-0.00836599
TYMP Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	thymine Metabolite (Entity type)
TYMP Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione Metabolite (Entity type)
TYMP Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	uracil Metabolite (Entity type)
2-Furan-2-yl-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYMP Gene (Entity type)	0.006256231
7-chloro-2-methyl-4-oxo-3-o-tolyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYMP Gene (Entity type)	-0.0037851196
SA-1922006 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TYMP Gene (Entity type)	-0.0126492195
Methyltyramine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TYMP Gene (Entity type)	0.014083327