ALDH6A1 (Gene)

Description: aldehyde dehydrogenase 6 family member A1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ALDH6A1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ALDH6A1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ALDH6A1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ALDH6A1.

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Gene Sets (725)

LINCS L1000 Chem Pert Consensus Sigs (452)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (263)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Decitabine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH6A1 Gene (Entity type)	-0.004049579
ALDH6A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate Metabolite (Entity type)
ALDH6A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	(S)-Methylmalonic acid semialdehyde Metabolite (Entity type)
ALDH6A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Propionyl-CoA Metabolite (Entity type)
N-(4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH6A1 Gene (Entity type)	-0.009990096
5-[2-methyl-5-[[3-(trifluoromethyl)phenyl]carbamoyl]anilino]pyridine-3-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH6A1 Gene (Entity type)	-0.0034596208
ALDH6A1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	NADP Metabolite (Entity type)
cyclopenthiazide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH6A1 Gene (Entity type)	-0.0076511614
Nepafenac Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDH6A1 Gene (Entity type)	-0.0031378726
bupivacaine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH6A1 Gene (Entity type)	0.004209319