ITPR1 (Gene)

Description: inositol 1,4,5-trisphosphate receptor type 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ITPR1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ITPR1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ITPR1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ITPR1.

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Gene Sets (683)

LINCS L1000 Chem Pert Consensus Sigs (349)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (7)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (5)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (311)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (7)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2,6-di-tert-butyl-4-methylphenol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITPR1 Gene (Entity type)	-0.04092945
Rasagiline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITPR1 Gene (Entity type)	0.002803108
FGIN-1-43 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITPR1 Gene (Entity type)	-0.0043532127
Anastrozole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITPR1 Gene (Entity type)	0.004075791
KFGENEBIN:ITPR1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ITPR1 Gene (Entity type)
phenyl-aminosalicylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITPR1 Gene (Entity type)	-0.03613902
aminoindazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITPR1 Gene (Entity type)	0.0101721715
H-7 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ITPR1 Gene (Entity type)	0.0057935095