PCSK6 (Gene)

Description: proprotein convertase subtilisin/kexin type 6

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PCSK6's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PCSK6.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PCSK6.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PCSK6.

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Gene Sets (921)

LINCS L1000 Chem Pert Consensus Sigs (474)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (426)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (3)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (9)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
EMF-sumo1-5 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	0.008604399
nizatidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	-0.005779291
US8987239, A::US9034856, A Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	-0.0030669954
2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	0.010270777
propylpyrazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	-0.010461956
KFGENEBIN:PCSK6-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)
BML-210 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	-0.015012477
Bicuculline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	0.011797906
potassium-canrenoate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	-0.002968613
HA-1004 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PCSK6 Gene (Entity type)	-0.003685333