CXCL8 (Gene)

Description: C-X-C motif chemokine ligand 8

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CXCL8's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CXCL8.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CXCL8.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CXCL8.

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Gene Sets (5059)

LINCS L1000 Chem Pert Consensus Sigs (2488)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (2537)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (28)

A gene set library provided by GTEx

IDG Drug Targets 2022 (5)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
bupivacaine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	-0.005877197
cinobufagin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.024412593
bufalin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.024853457
CHIR-99021 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.0072095613
SA-1921574 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	-0.016100606
Tolazamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	-0.003995507
(2,3-dichlorophenyl)(5-methoxy-2-methyl-3-(2-morpholinoethyl)-1H-indol-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.007863443
UTMB-00042 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	-0.010370567
5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[2,3'']bipyridinyl Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	-0.0032489253
KU-C103871 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	0.012424654