PTTG1 (Gene)

Description: PTTG1 regulator of sister chromatid separation, securin

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PTTG1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PTTG1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PTTG1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PTTG1.

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Gene Sets (1099)

LINCS L1000 Chem Pert Consensus Sigs (610)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (9)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (470)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
RG7112 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	-0.0063949763
KUC111109N Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	-0.003547103
KFGENEBIN:PTTG1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)
Rolipram Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	0.0035803716
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	-0.004305413
SID11113665 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	-0.009960146
AS-605240 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	0.0028099185
EI-247 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	0.007993375
CGP-37157 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	0.004662608
3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PTTG1 Gene (Entity type)	0.0034824237