SPINK1 (Gene)

Description: serine peptidase inhibitor Kazal type 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SPINK1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SPINK1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SPINK1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SPINK1.

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Gene Sets (3695)

LINCS L1000 Chem Pert Consensus Sigs (1915)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1742)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (26)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
BML-190 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.01047863
N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.0039364924
SA-419172 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.013320655
Domperidone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.009298705
lacosamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.0056955847
3-Bicyclo[2.2.1]hept-5-en-2-yl-7-chloro-1,1-dioxo-1,2,3,4-tetrahydro-1lambda6-benzo[1,2,4]thiadiazine-6-sulfonic acid amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.04172793
SID14726526 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.016318873
Fusaric-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.012161686
MW-STK33-3A Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.009464858
hippeastrine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.010915396