TMEM106B (Gene)

Description: transmembrane protein 106B

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TMEM106B's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TMEM106B.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TMEM106B.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TMEM106B.

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Gene Sets (809)

LINCS L1000 Chem Pert Consensus Sigs (218)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (9)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (19)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (7)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (556)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(S)-1-[2-(3-Hydroxy-adamantan-1-ylamino)-acetyl]-pyrrolidine-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM106B Gene (Entity type)	0.004374779
urethane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM106B Gene (Entity type)	-0.012284414
compound 5b [PMID: 16686537] Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM106B Gene (Entity type)	-0.0054131183
BMS-833923 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM106B Gene (Entity type)	-0.008369479
KFGENEBIN:TMEM106B-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	TMEM106B Gene (Entity type)
Dipeptidyl boronic acid derivative Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM106B Gene (Entity type)	-0.006189177
Pentobarbital Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM106B Gene (Entity type)	-0.0042967275