LYN (Gene)

Description: LYN proto-oncogene, Src family tyrosine kinase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LYN's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LYN.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LYN.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LYN.

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Gene Sets (1715)

LINCS L1000 Chem Pert Consensus Sigs (750)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (17)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (17)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (906)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

IDG Drug Targets 2022 (22)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
cebranopadol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	-0.020525107
isopropyl 4-(1-(2-fluoro-4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	0.0064036264
repaglinide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	-0.0037310957
Methenamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	-0.013838575
Oxiconazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	0.0046276273
SA-1920013 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	-0.00903746
SID11114136 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	0.0043239277
efaproxiral Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	-0.0038064169
Acrivastine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	-0.0054827896
2-iminobiotin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LYN Gene (Entity type)	-0.0054181335