NNT (Gene)

Description: nicotinamide nucleotide transhydrogenase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NNT's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NNT.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NNT.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NNT.

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Gene Sets (536)

LINCS L1000 Chem Pert Consensus Sigs (230)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (11)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (288)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
MW-STK33-2B Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	0.010712219
Atractyloside Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	-0.021456543
lasalocid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	0.0074186595
givinostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	-0.010212648
NNT Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nicotinamide adenine dinucleotide (NAD) Metabolite (Entity type)
N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	0.020300068
Resminostat; (E)-3-(1-((4-((dimethylamino)methyl)phenyl)sulfonyl)-1H-pyrrol-3-yl)-N-hydroxyacrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	-0.0059646363
BG-STK33-03 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	0.018613024
MW-STK33-100 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	0.013725074
Sulfamethizole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NNT Gene (Entity type)	0.020108357