A2M (Gene)

Description: alpha-2-macroglobulin

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View A2M's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with A2M.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using A2M.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for A2M.

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Gene Sets (2688)

LINCS L1000 Chem Pert Consensus Sigs (1258)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (11)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1401)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SA-427069 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	-0.011446572
KM-00519SC Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.014188139
SA-1472321 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	-0.009878422
SID11114140 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.007768329
Isoquercitrin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.0120741455
SA-1921996 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.021472443
Trequinsin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.003872474
propofol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.005235283
EMD-84 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.009298149
sufinpyrazone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	A2M Gene (Entity type)	0.00964894