PAK1 (Gene)

Description: p21 (RAC1) activated kinase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PAK1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PAK1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PAK1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PAK1.

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Gene Sets (2342)

LINCS L1000 Chem Pert Consensus Sigs (1224)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (5)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1103)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (5)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Balaglitazone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	0.004741959
VU-0415012 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	-0.014648467
Sulfadoxine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	-0.009073975
dioscin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	0.02656982
JAS07-009 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	-0.00892215
SID11114027 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	0.009759195
SID11112246 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	0.0068133543
glemanserin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	-0.013136723
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	-0.009095088
1-{5-Ethyl-2-hydroxy-4-[6-methyl-6-(2H-tetrazol-5-yl)-heptyloxy]-phenyl}-ethanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	0.012134697