PAICS (Gene)

Description: phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PAICS's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PAICS.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PAICS.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PAICS.

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Gene Sets (339)

LINCS L1000 Chem Pert Consensus Sigs (212)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (10)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (113)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
PAICS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Adenosine Diphosphate Metabolite (Entity type)
PAICS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	SAICAR Metabolite (Entity type)
KFGENEBIN:PAICS-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PAICS Gene (Entity type)
PAICS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ADP Metabolite (Entity type)
PAICS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	5-Aminoimidazole ribonucleotide Metabolite (Entity type)
ethaverine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAICS Gene (Entity type)	-0.0065642926
Troglitazone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PAICS Gene (Entity type)	0.0024801863
DAC-012 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PAICS Gene (Entity type)	0.013292116
PAICS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Aspartic Acid Metabolite (Entity type)
PAICS Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	aspartic acid Metabolite (Entity type)