TRPM4 (Gene)

Description: transient receptor potential cation channel subfamily M member 4

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TRPM4's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TRPM4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TRPM4.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TRPM4.

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Gene Sets (61879)

LINCS L1000 Chem Pert Consensus Sigs (376)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

LINCS L1000 CRISPR KO Consensus Sigs (260)

A gene set library provided by LINCS

l1000 cp (60403)

A gene set library provided by LINCS

IDG Drug Targets 2022 (4)

A gene set library provided by IDG

rummageo gene perturbations (133)

A gene set library provided by LINCS

rummageo chemical perturbations (233)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

GTEx Tissues V8 2023 (4)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (457)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.0043794583
(10R,13S)-17-Eth-(Z)-ylidene-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,16-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.008690338
AM251 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	0.006078674
US8987239, A::US9034856, A Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	0.0033338836
Alectinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.0043287533
napelline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.009163377
Efatutazone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.0074436218
{2-methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-phenoxy}-acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.0054293554
tolfenamic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.0037590375
PQ401 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	0.0055176527