DHTKD1 (Gene)

Description: dehydrogenase E1 and transketolase domain containing 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DHTKD1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DHTKD1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DHTKD1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DHTKD1.

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Gene Sets (598)

LINCS L1000 Chem Pert Consensus Sigs (265)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (329)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
DHTKD1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nadide Metabolite (Entity type)
Ripasudil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHTKD1 Gene (Entity type)	0.0043762997
KFGENEBIN:DHTKD1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	DHTKD1 Gene (Entity type)
DHTKD1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nicotinamide adenine dinucleotide (NAD) Metabolite (Entity type)
DHTKD1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate Metabolite (Entity type)
2-chloro-4-((1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-yl)ethynyl)pyridine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHTKD1 Gene (Entity type)	-0.0034926224
DHTKD1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Oxoadipic acid Metabolite (Entity type)
DHTKD1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	coenzyme A Metabolite (Entity type)
DHTKD1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Glutaryl-CoA Metabolite (Entity type)