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Somatostatin receptor type 4 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Somatostatin receptor type 4 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	5-{(2S,3S,4R,5R,6S)-3,4-Bis-benzyloxy-5-(1H-imidazol-4-ylmethoxy)-6-[2-(1H-indol-3-yl)-ethoxy]-tetrahydro-pyran-2-ylmethoxy}-pentylamine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	Ki
	1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)-amino]-ethyl}-3-[3-(1H-imidazol-4-yl)-propyl]-thiourea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	Ki
	(2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,37S,Z)-14-((1H-indol-3-yl)methyl)-5-(2-amino-2-oxoethyl)-2,17-bis(4-aminobutyl)-37-(2-((S)-2-aminopropanamido)acetamido)-8,11,23-tribenzyl-20,26-bis((R)-1-hydroxyethyl)-29-(hydroxymethyl)-3,6,9,12,15,18,21,24,27,30,38-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclooctatriacont-34-ene-32-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	Ki
	1-(3-(1H-imidazol-5-yl)propyl)-3-(3-((5-bromopyridin-2-yl)(4-chlorobenzyl)amino)propyl)-1-methylthiourea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	Ki
	(5S)-6-oxo-5-[(4R)-3-oxo-4-[(phenylacetyl)amino]-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]-6-[(2-phenylethyl)amino]hexan-1-aminium trifluoroacetate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	IC50
	(5R)-6-(benzylamino)-6-oxo-5-[(4R)-3-oxo-4-[(phenylacetyl)amino]-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]hexan-1-aminium trifluoroacetate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	IC50
	3-(2-(4-(3-(1H-Imidazol-4-yl)propyl)-5-(3,4-dichlorobenzyl)-4H-1,2,4-triazol-3-yl)ethyl)-1H-indole Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	EC50
	(5S)-6-(benzylamino)-6-oxo-5-((4R)-3-oxo-4-(4-(phenylsulfonyl)piperazine-1-carboxamido)-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)hexan-1-aminium trifluoroacetate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	IC50
	(2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacetyl)amino]-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]hexanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	IC50
	2N-(4-bromobenzyl)-2N-(3-{1-[3-(1H-4-imidazolyl)propylimino]methylthioamino}propyl)-2-pyridinamine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 4 Protein (Entity type)	Ki

5-{(2S,3S,4R,5R,6S)-3,4-Bis-benzyloxy-5-(1H-imidazol-4-ylmethoxy)-6-[2-(1H-indol-3-yl)-ethoxy]-tetrahydro-pyran-2-ylmethoxy}-pentylamine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
Ki

1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)-amino]-ethyl}-3-[3-(1H-imidazol-4-yl)-propyl]-thiourea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
Ki

(2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,37S,Z)-14-((1H-indol-3-yl)methyl)-5-(2-amino-2-oxoethyl)-2,17-bis(4-aminobutyl)-37-(2-((S)-2-aminopropanamido)acetamido)-8,11,23-tribenzyl-20,26-bis((R)-1-hydroxyethyl)-29-(hydroxymethyl)-3,6,9,12,15,18,21,24,27,30,38-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclooctatriacont-34-ene-32-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
Ki

1-(3-(1H-imidazol-5-yl)propyl)-3-(3-((5-bromopyridin-2-yl)(4-chlorobenzyl)amino)propyl)-1-methylthiourea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
Ki

(5S)-6-oxo-5-[(4R)-3-oxo-4-[(phenylacetyl)amino]-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]-6-[(2-phenylethyl)amino]hexan-1-aminium trifluoroacetate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
IC50

(5R)-6-(benzylamino)-6-oxo-5-[(4R)-3-oxo-4-[(phenylacetyl)amino]-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]hexan-1-aminium trifluoroacetate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
IC50

3-(2-(4-(3-(1H-Imidazol-4-yl)propyl)-5-(3,4-dichlorobenzyl)-4H-1,2,4-triazol-3-yl)ethyl)-1H-indole
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
EC50

(5S)-6-(benzylamino)-6-oxo-5-((4R)-3-oxo-4-(4-(phenylsulfonyl)piperazine-1-carboxamido)-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)hexan-1-aminium trifluoroacetate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
IC50

(2S)-6-amino-N-benzyl-2-[(4R)-3-oxo-4-[(phenylacetyl)amino]-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]hexanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
IC50

2N-(4-bromobenzyl)-2N-(3-{1-[3-(1H-4-imidazolyl)propylimino]methylthioamino}propyl)-2-pyridinamine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 4
Protein (Entity type)
Ki

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