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Prostaglandin E2 receptor EP3 subtype (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Prostaglandin E2 receptor EP3 subtype 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-fluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)acrylamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	IC50
	3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	IC50
	US9278953, 6 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	Ki
	methyl 1-(2,4-dichlorobenzyl)-2-oxo-7-(3-oxo-3-(2,4,5-trifluorophenylsulfonamido)prop-1-enyl)-2,3,3a,4,5,6-hexahydro-1H-indole-3a-carboxylate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	IC50
	2-(3-(naphthalen-2-ylsulfonyl)-1H-indol-4-yloxy)-N-(thiophen-2-ylsulfonyl)acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	IC50
	Thiophene-2-sulfonic Acid{(E)-3-[1-(3-Trifluoromethylbenzyl)-1H-indol-7-yl]acryloyl}amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	IC50
	3,4-Difluoro-N-{(E)-3-[5-fluoro-1-(3-methoxybenzyl)-3-methyl-1H-indol-7-yl]acryloyl}benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	IC50
	N-(3,4-difluorophenylsulfonyl)-3-(3-methyl-1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)acrylamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	IC50
	3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	IC50
	(E)-3-{2-[(E)-3-(4-Methoxy-phenyl)-allyl]-phenyl}-acrylic acid; compound with (E)-3-{2-[(E)-3-(4-methoxy-phenyl)-propenyl]-phenyl}-acrylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Prostaglandin E2 receptor EP3 subtype Protein (Entity type)	Ki

N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-fluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)acrylamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
IC50

3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
IC50

US9278953, 6
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
Ki

methyl 1-(2,4-dichlorobenzyl)-2-oxo-7-(3-oxo-3-(2,4,5-trifluorophenylsulfonamido)prop-1-enyl)-2,3,3a,4,5,6-hexahydro-1H-indole-3a-carboxylate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
IC50

2-(3-(naphthalen-2-ylsulfonyl)-1H-indol-4-yloxy)-N-(thiophen-2-ylsulfonyl)acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
IC50

Thiophene-2-sulfonic Acid{(E)-3-[1-(3-Trifluoromethylbenzyl)-1H-indol-7-yl]acryloyl}amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
IC50

3,4-Difluoro-N-{(E)-3-[5-fluoro-1-(3-methoxybenzyl)-3-methyl-1H-indol-7-yl]acryloyl}benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
IC50

N-(3,4-difluorophenylsulfonyl)-3-(3-methyl-1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)acrylamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
IC50

3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
IC50

(E)-3-{2-[(E)-3-(4-Methoxy-phenyl)-allyl]-phenyl}-acrylic acid; compound with (E)-3-{2-[(E)-3-(4-methoxy-phenyl)-propenyl]-phenyl}-acrylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Prostaglandin E2 receptor EP3 subtype
Protein (Entity type)
Ki

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