Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-Ethoxy-N-(6-hydroxyhexyl)-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	IC50
3-isopropyl-1-methyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	IC50
US9073936, 3 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	Ki
(S)-4-(6-chloro-2,3-dihydro-1H-inden-1-yl)-7,8-dimethoxyquinazoline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	IC50
(S)-7,8-Dimethoxy-N-(1-(5-methyl-1H-pyrazol-3-yl)propan-2-yl)quinazolin-4-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	IC50
US8829000, Referential Example 1 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	IC50
US9073936, 4 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	Ki
O-(4-Ethoxybutyl)berbamine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	IC50
(+/-)-7,8-Dimethoxy-N-(1-(5-methyl-1H-pyrazol-3-yl)propan-2-yl)quinazolin-4-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	IC50
SCH51866 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein (Entity type)	IC50

4-Ethoxy-N-(6-hydroxyhexyl)-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
IC50

3-isopropyl-1-methyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
IC50

US9073936, 3
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
Ki

(S)-4-(6-chloro-2,3-dihydro-1H-inden-1-yl)-7,8-dimethoxyquinazoline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
IC50

(S)-7,8-Dimethoxy-N-(1-(5-methyl-1H-pyrazol-3-yl)propan-2-yl)quinazolin-4-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
IC50

US8829000, Referential Example 1
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
IC50

US9073936, 4
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
Ki

O-(4-Ethoxybutyl)berbamine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
IC50

(+/-)-7,8-Dimethoxy-N-(1-(5-methyl-1H-pyrazol-3-yl)propan-2-yl)quinazolin-4-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
IC50

SCH51866
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Protein (Entity type)
IC50

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