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Catenin beta-1 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Catenin beta-1 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	SID22405070 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	IC50
	Catenin beta-1 Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:P35222-1 CUI Isoform (Entity type)
	3',4'-difluoro-N-(4'-fluoro-6-((S)-pyrrolidin-3-yloxy)biphenyl-3-yl)-6-((S)-pyrrolidin-3-yloxy)biphenyl-3-carboxamide dihydrochloride Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	Ki
	(S)-4-((S)-2-((S)-2-(4,6-Dichloro-1H-indole-2-carboxamido)-3-(naphthalen-2-yl)propanamido)-3-(2H-tetrazol-5-yl)-propanamido)-5-oxo-5-((4-(trifluoromethoxy)phenyl)amino)pentanoic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	Ki
	2-((3S,6S,9S,12S,21S,Z)-21-((6S,9S,12S,15S,18S,21S,24S)-9-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-15,18-bis(3-guanidinopropyl)-25-(1H-imidazol-5-yl)-1-imino-12,21-diisopropyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-ylcarbamoyl)-12-((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-5-guanidinopentanamido)-3-(1H-indol-3-yl)propanoyl)pyrrolidine-2-carboxamido)-5-amino-5-oxopentanamido)-9-sec-butyl-6-isobutyl-12,21-dimethyl-2,5,8,11-tetraoxo-1,4,7,10-tetraazacyclohenicos-16-en-3-yl)acetic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	Kd
	(6S,9S,12S,15S)-1,19-diamino-6-((S)-5-amino-2-((S)-2-((S)-2-((2S,5S,8S,11S,20S,Z)-20-((S)-2-((S)-1-((S)-4-amino-2-((S)-2-((S)-2-amino-4-carboxybutanamido)-4-carboxybutanamido)-4-oxobutanoyl)pyrrolidine-2-carboxamido)-4-carboxybutanamido)-2-sec-butyl-8-(carboxymethyl)-5-isobutyl-11,20-dimethyl-3,6,9,21-tetraoxo-1,4,7,10-tetraazacyclohenicos-15-enecarboxamido)-3-(1H-imidazol-5-yl)propanamido)-3-methylbutanamido)-5-oxopentanamido)-1-imino-9-isopropyl-12-(2-(methylthio)ethyl)-7,10,13-trioxo-2,8,11,14-tetraazanonadecane-15-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	Kd
	(S)-4-((S)-2-((S)-2-(5-Chloro-1H-indole-2-carboxamido)-3-(naphthalen-2-yl)propanamido)-3-(2H-tetrazol-5-yl)propanamido)-5-oxo-5-((4-(trifluoromethoxy)phenyl)amino)pentanoic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	Ki
	N'-((5-methylfuran-2-yl)methylene)-2-phenoxybenzohydrazide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	Kd
	2-((3S,6S,9S,12S,21S,Z)-21-((6S,9S,12S,15S,18S,21S,24S)-9-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-15,18-bis(3-guanidinopropyl)-25-(1H-imidazol-5-yl)-1-imino-12,21-diisopropyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-ylcarbamoyl)-12-((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-5-guanidinopentanamido)-3-(1H-indol-3-yl)propanoyl)pyrrolidine-2-carboxamido)-5-guanidinopentanamido)-9-sec-butyl-6-isobutyl-12,21-dimethyl-2,5,8,11-tetraoxo-1,4,7,10-tetraazacyclohenicos-16-en-3-yl)acetic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	Kd
	SID14728191 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Catenin beta-1 Protein (Entity type)	IC50

SID22405070
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
IC50

Catenin beta-1
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:P35222-1 CUI
Isoform (Entity type)

3',4'-difluoro-N-(4'-fluoro-6-((S)-pyrrolidin-3-yloxy)biphenyl-3-yl)-6-((S)-pyrrolidin-3-yloxy)biphenyl-3-carboxamide dihydrochloride
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
Ki

(S)-4-((S)-2-((S)-2-(4,6-Dichloro-1H-indole-2-carboxamido)-3-(naphthalen-2-yl)propanamido)-3-(2H-tetrazol-5-yl)-propanamido)-5-oxo-5-((4-(trifluoromethoxy)phenyl)amino)pentanoic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
Ki

2-((3S,6S,9S,12S,21S,Z)-21-((6S,9S,12S,15S,18S,21S,24S)-9-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-15,18-bis(3-guanidinopropyl)-25-(1H-imidazol-5-yl)-1-imino-12,21-diisopropyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-ylcarbamoyl)-12-((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-5-guanidinopentanamido)-3-(1H-indol-3-yl)propanoyl)pyrrolidine-2-carboxamido)-5-amino-5-oxopentanamido)-9-sec-butyl-6-isobutyl-12,21-dimethyl-2,5,8,11-tetraoxo-1,4,7,10-tetraazacyclohenicos-16-en-3-yl)acetic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
Kd

(6S,9S,12S,15S)-1,19-diamino-6-((S)-5-amino-2-((S)-2-((S)-2-((2S,5S,8S,11S,20S,Z)-20-((S)-2-((S)-1-((S)-4-amino-2-((S)-2-((S)-2-amino-4-carboxybutanamido)-4-carboxybutanamido)-4-oxobutanoyl)pyrrolidine-2-carboxamido)-4-carboxybutanamido)-2-sec-butyl-8-(carboxymethyl)-5-isobutyl-11,20-dimethyl-3,6,9,21-tetraoxo-1,4,7,10-tetraazacyclohenicos-15-enecarboxamido)-3-(1H-imidazol-5-yl)propanamido)-3-methylbutanamido)-5-oxopentanamido)-1-imino-9-isopropyl-12-(2-(methylthio)ethyl)-7,10,13-trioxo-2,8,11,14-tetraazanonadecane-15-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
Kd

(S)-4-((S)-2-((S)-2-(5-Chloro-1H-indole-2-carboxamido)-3-(naphthalen-2-yl)propanamido)-3-(2H-tetrazol-5-yl)propanamido)-5-oxo-5-((4-(trifluoromethoxy)phenyl)amino)pentanoic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
Ki

N'-((5-methylfuran-2-yl)methylene)-2-phenoxybenzohydrazide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
Kd

2-((3S,6S,9S,12S,21S,Z)-21-((6S,9S,12S,15S,18S,21S,24S)-9-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-15,18-bis(3-guanidinopropyl)-25-(1H-imidazol-5-yl)-1-imino-12,21-diisopropyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-ylcarbamoyl)-12-((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-5-guanidinopentanamido)-3-(1H-indol-3-yl)propanoyl)pyrrolidine-2-carboxamido)-5-guanidinopentanamido)-9-sec-butyl-6-isobutyl-12,21-dimethyl-2,5,8,11-tetraoxo-1,4,7,10-tetraazacyclohenicos-16-en-3-yl)acetic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
Kd

SID14728191
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Catenin beta-1
Protein (Entity type)
IC50

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