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Type-2 angiotensin II receptor (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Type-2 angiotensin II receptor 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	N-{3-[3-Butyl-5-oxo-4-(2'-(N-t-butyloxycarbonyl)-Sulfanamido-biphenyl-4-ylmethyl)-4,5-dihydro-[1,2,4]triazol-1-yl]-4-trifluoromethyl-phenyl}-propionamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	IC50
	3-[3-Butyl-4-(3-fluoro-2'-(N-t-butyloxycarbonyl)-Sulfanamido-biphenyl-4-ylmethyl)-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl]-4-chloro-N-(2-methoxy-ethyl)-benzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	IC50
	N-butylaminocarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	Ki
	(3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-2-[(2S)-butan-2-yl]-4-({[(2S)-1-[(2S)-2-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}pyrrolidin-1-yl]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]carbamoyl}methyl)-9-[(4-hydroxyphenyl)methyl]-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-7-yl]carbamoyl}-2-methylpropyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}propanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	Ki
	2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(ethylaminocarbonylamino)-3H-quinazolin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	IC50
	1-((2'-(N-benzoylsulfamoyl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	IC50
	4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-3'-fluoro-biphenyl-2-sulfonic acid 4-ethyl-benzoylamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	IC50
	4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-sulfonic acid benzoylamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	IC50
	4'-[(6-Phenylacetylamino-4-methyl-2-n-propyl-1H-benzimidazol-1-yl)methyl]biphenyl-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	IC50
	N-(N-butyl-methylaminocarbonyl)-3-(4-imidazol-1-ylmethylphenyl)-5-isobutylthiophene-2-sulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Type-2 angiotensin II receptor Protein (Entity type)	Ki

N-{3-[3-Butyl-5-oxo-4-(2'-(N-t-butyloxycarbonyl)-Sulfanamido-biphenyl-4-ylmethyl)-4,5-dihydro-[1,2,4]triazol-1-yl]-4-trifluoromethyl-phenyl}-propionamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
IC50

3-[3-Butyl-4-(3-fluoro-2'-(N-t-butyloxycarbonyl)-Sulfanamido-biphenyl-4-ylmethyl)-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl]-4-chloro-N-(2-methoxy-ethyl)-benzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
IC50

N-butylaminocarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
Ki

(3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-2-[(2S)-butan-2-yl]-4-({[(2S)-1-[(2S)-2-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}pyrrolidin-1-yl]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]carbamoyl}methyl)-9-[(4-hydroxyphenyl)methyl]-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-7-yl]carbamoyl}-2-methylpropyl]carbamoyl}-4-[(diaminomethylidene)amino]butyl]carbamoyl}propanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
Ki

2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(ethylaminocarbonylamino)-3H-quinazolin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
IC50

1-((2'-(N-benzoylsulfamoyl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
IC50

4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-3'-fluoro-biphenyl-2-sulfonic acid 4-ethyl-benzoylamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
IC50

4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-sulfonic acid benzoylamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
IC50

4'-[(6-Phenylacetylamino-4-methyl-2-n-propyl-1H-benzimidazol-1-yl)methyl]biphenyl-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
IC50

N-(N-butyl-methylaminocarbonyl)-3-(4-imidazol-1-ylmethylphenyl)-5-isobutylthiophene-2-sulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Type-2 angiotensin II receptor
Protein (Entity type)
Ki

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