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Metabotropic glutamate receptor 4 (Protein)

Description: A protein in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Metabotropic glutamate receptor 4 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	3-Cyclopropyl-N-(1H-pyrazolo[3,4-b]pyrazin-3-yl)benzo[d]isothiazol-6-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	US9192603, 32 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	6-(3-Pyridin-3-yl-propoxy)-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one Oxime Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	N-[3-cyclopropyl-1-(2,2,2-trideuterioethyl)indazol-6-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	(5,7-Dihydro-4H-3-thia-1,6,7-triaza-as-indacen-2-yl)-pyrimidin-2-yl-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	6-(2'-Methyl-3,4,5,6-tetrahydro-2H-[1,3']bipyridinyl-4-ylmethyl)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one Oxime Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	6-(2-Morpholin-4-yl-ethoxy)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one Oxime Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	3-amino-N-(3-chloro-4-(3-oxo-2-azaspiro[4.5]decan-2-yl)phenyl)picolinamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	(6-((1H-Pyrazolo[4,3-b]pyridin-3-yl)amino)benzo[d]isothiazol-3-yl)(4,4-difluoropiperidin-1-yl)methanone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50
	US9192603, 6 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Metabotropic glutamate receptor 4 Protein (Entity type)	EC50

3-Cyclopropyl-N-(1H-pyrazolo[3,4-b]pyrazin-3-yl)benzo[d]isothiazol-6-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

US9192603, 32
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

6-(3-Pyridin-3-yl-propoxy)-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one Oxime
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

N-[3-cyclopropyl-1-(2,2,2-trideuterioethyl)indazol-6-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

(5,7-Dihydro-4H-3-thia-1,6,7-triaza-as-indacen-2-yl)-pyrimidin-2-yl-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

6-(2'-Methyl-3,4,5,6-tetrahydro-2H-[1,3']bipyridinyl-4-ylmethyl)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one Oxime
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

6-(2-Morpholin-4-yl-ethoxy)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one Oxime
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

3-amino-N-(3-chloro-4-(3-oxo-2-azaspiro[4.5]decan-2-yl)phenyl)picolinamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

(6-((1H-Pyrazolo[4,3-b]pyridin-3-yl)amino)benzo[d]isothiazol-3-yl)(4,4-difluoropiperidin-1-yl)methanone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

US9192603, 6
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Metabotropic glutamate receptor 4
Protein (Entity type)
EC50

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025