Programmed cell death 1 ligand 1 (Protein)

Description: A protein in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Programmed cell death 1 ligand 1 's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(2R)-2-[({2,6-Dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]-phenyl}methyl)amino]-3-methylbutan-1-ol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	IC50
N-{2-[({2,6-Dimethoxy-4-[(2-methyl-3-phenylphenylmethoxy]-phenyl}methyl)amino]ethyl}acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	IC50
(3S,14S,17S,20S,23S,26S,35S,38S,41S)-14,17-bis((1H-indol-3-yl)methyl)-N,41-bis(2-amino-2-oxoethyl)-35-benzyl-20,23-dibutyl-26-(3-guanidinopropyl)-3-isobutyl-7,19,22,37,38-pentamethyl-1,4,6,9,12,15,18,21,24,27,33,36,39,42-tetradecaoxotetratetracontahydro-1H-pyrrolo[1,2-m][1,4,7,10,13,16,19,21,24,27,30,33,36,39,42]thiatetradecaazacyclotetratetracontine-29-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	IC50
BMS-202 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	IC50
Programmed cell death 1 ligand 1 Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:Q9NZQ7-1 CUI Isoform (Entity type)
(R)-2-(2-((5-cyanopyridin-3-yl)methoxy)-4-((2-methylbiphenyl-3-yl)methoxy)benzylamino)-3-hydroxypropanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	Kd
1-({3-Bromo-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl}-methyl)piperidine-2-carboxylic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	IC50
(2R)-2-[({2-[(3-Cyanophenyl)methoxy]-4-{[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy}-5-methylphenyl}-methyl)amino]-3-hydroxypropanoic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	IC50
(4-((3'-((4-((((R)-1-Carboxy-2-hydroxyethyl)amino)methyl)-3-((5-cyanopyridin-3-yl)methoxy)phenoxy)methyl)-2,2'-dimethyl-[1,1'-biphenyl]-3-yl)methoxy)-2-methoxybenzyl)-D-serine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	Kd
N-(2-hydroxyethyl)-1-(3-methyl-4-((2-methylbiphenyl-3-yl)methoxy)benzyl)piperidine-4-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Programmed cell death 1 ligand 1 Protein (Entity type)	IC50

(2R)-2-[({2,6-Dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]-phenyl}methyl)amino]-3-methylbutan-1-ol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
IC50

N-{2-[({2,6-Dimethoxy-4-[(2-methyl-3-phenylphenylmethoxy]-phenyl}methyl)amino]ethyl}acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
IC50

(3S,14S,17S,20S,23S,26S,35S,38S,41S)-14,17-bis((1H-indol-3-yl)methyl)-N,41-bis(2-amino-2-oxoethyl)-35-benzyl-20,23-dibutyl-26-(3-guanidinopropyl)-3-isobutyl-7,19,22,37,38-pentamethyl-1,4,6,9,12,15,18,21,24,27,33,36,39,42-tetradecaoxotetratetracontahydro-1H-pyrrolo[1,2-m][1,4,7,10,13,16,19,21,24,27,30,33,36,39,42]thiatetradecaazacyclotetratetracontine-29-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
IC50

BMS-202
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
IC50

Programmed cell death 1 ligand 1
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:Q9NZQ7-1 CUI
Isoform (Entity type)

(R)-2-(2-((5-cyanopyridin-3-yl)methoxy)-4-((2-methylbiphenyl-3-yl)methoxy)benzylamino)-3-hydroxypropanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
Kd

1-({3-Bromo-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl}-methyl)piperidine-2-carboxylic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
IC50

(2R)-2-[({2-[(3-Cyanophenyl)methoxy]-4-{[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy}-5-methylphenyl}-methyl)amino]-3-hydroxypropanoic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
IC50

(4-((3'-((4-((((R)-1-Carboxy-2-hydroxyethyl)amino)methyl)-3-((5-cyanopyridin-3-yl)methoxy)phenoxy)methyl)-2,2'-dimethyl-[1,1'-biphenyl]-3-yl)methoxy)-2-methoxybenzyl)-D-serine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
Kd

N-(2-hydroxyethyl)-1-(3-methyl-4-((2-methylbiphenyl-3-yl)methoxy)benzyl)piperidine-4-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Programmed cell death 1 ligand 1
Protein (Entity type)
IC50

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.