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Cathepsin G (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Cathepsin G 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(6R,7R)-3-(4-Carboxymethyl-4H-[1,2,4]triazol-3-ylsulfanylmethyl)-7-methoxy-7-(2-methoxy-benzoylamino)-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-methyl-benzyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	IC50
	(4S)-4-((S)-2-amino-3-carboxypropanamido)-5-oxo-5-(1-oxo-1-((S)-1-oxo-3-phenylpropan-2-ylamino)hexan-2-ylamino)pentanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	Ki
	compound 4g [PMID: 22595175] Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	IC50
	3-[(7R,10S,16S,19S,22S,25R,28R,31S,34S,37S,40S,43S,46S,49R)-49-[(2S)-2-aminopropanamido]-10-benzyl-16,43-bis(3-carbamimidamidopropyl)-37-(2-carbamoylethyl)-7-[(carbamoylmethyl)carbamoyl]-19,31-bis(carboxymethyl)-22-[(4-hydroxyphenyl)methyl]-40-methyl-46-(2-methylpropyl)-9,12,15,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-25-(propan-2-yl)-5,51,56-trithia-8,11,14,17,20,23,26,29,32,35,38,41,44,47-tetradecaazatricyclo[26.26.3.1^{3,53}]octapentaconta-1(54),2,53(58)-trien-34-yl]propanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	IC50
	(3S)-3-amino-4-((2S,3R)-3-hydroxy-1-oxo-1-(1-oxo-1-((S)-1-oxo-3-phenylpropan-2-ylamino)hexan-2-ylamino)butan-2-ylamino)-4-oxobutanoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	Ki
	PUBCHEM:155568945 CUI Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	Ki
	3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	IC50
	1,1-dimethyl-2-phenylcarboxamidopropanoic anhydride Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	IC50
	PUBCHEM:137652632 CUI Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	Ki
	Peptide boronate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cathepsin G Protein (Entity type)	Ki

(6R,7R)-3-(4-Carboxymethyl-4H-[1,2,4]triazol-3-ylsulfanylmethyl)-7-methoxy-7-(2-methoxy-benzoylamino)-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-methyl-benzyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
IC50

(4S)-4-((S)-2-amino-3-carboxypropanamido)-5-oxo-5-(1-oxo-1-((S)-1-oxo-3-phenylpropan-2-ylamino)hexan-2-ylamino)pentanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
Ki

compound 4g [PMID: 22595175]
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
IC50

3-[(7R,10S,16S,19S,22S,25R,28R,31S,34S,37S,40S,43S,46S,49R)-49-[(2S)-2-aminopropanamido]-10-benzyl-16,43-bis(3-carbamimidamidopropyl)-37-(2-carbamoylethyl)-7-[(carbamoylmethyl)carbamoyl]-19,31-bis(carboxymethyl)-22-[(4-hydroxyphenyl)methyl]-40-methyl-46-(2-methylpropyl)-9,12,15,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-25-(propan-2-yl)-5,51,56-trithia-8,11,14,17,20,23,26,29,32,35,38,41,44,47-tetradecaazatricyclo[26.26.3.1^{3,53}]octapentaconta-1(54),2,53(58)-trien-34-yl]propanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
IC50

(3S)-3-amino-4-((2S,3R)-3-hydroxy-1-oxo-1-(1-oxo-1-((S)-1-oxo-3-phenylpropan-2-ylamino)hexan-2-ylamino)butan-2-ylamino)-4-oxobutanoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
Ki

PUBCHEM:155568945 CUI
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
Ki

3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
IC50

1,1-dimethyl-2-phenylcarboxamidopropanoic anhydride
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
IC50

PUBCHEM:137652632 CUI
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
Ki

Peptide boronate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cathepsin G
Protein (Entity type)
Ki

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