Mannan-binding lectin serine protease 1 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Mannan-binding lectin serine protease 1 's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(2S,5S,8R,11S,14S,17S,20S,23R,26S,29S,32S,35S,41S,44S,50R,53S,56R,59S,62S,65R,68S,71S)-62-(2-amino-2-oxoethyl)-71-((6S,9S,12S,15S)-1-((S)-1-((S)-2-((R)-2-((2S,3R)-2-((S)-2-amino-3-methylbutanamido)-3-hydroxybutanamido)-3-mercaptopropanamido)-4-carboxybutanoyl)pyrrolidin-2-yl)-15-(4-aminobutyl)-12-benzyl-6,9-bis((R)-1-hydroxyethyl)-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecanamido)-2-(3-amino-3-oxopropyl)-14,35,68-tris(4-aminobutyl)-26-benzyl-41-(carboxymethyl)-17,53-bis(3-guanidinopropyl)-5-(4-hydroxybenzyl)-20,59-bis((R)-1-hydroxyethyl)-32,44-bis(hydroxymethyl)-11-isobutyl-8,23,50,56,65-pentakis(mercaptomethyl)-29-methyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70-tricosaoxo-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-tricosaazatriheptacontane-1,73-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mannan-binding lectin serine protease 1 Protein (Entity type)	Ki
(S)-2-((S)-1-((2S,3S)-2-((R)-2-((2S,3S)-2-((S)-1-((S)-1-((2S,5S,8S,11S,14R,17S)-20-amino-17-sec-butyl-8-(3-guanidinopropyl)-5,11-bis(hydroxymethyl)-2-isobutyl-14-(mercaptomethyl)-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazaicosane)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-3-methylpentanamido)-3-mercaptopropanamido)-3-methylpentanoyl)pyrrolidine-2-carboxamido)succinic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mannan-binding lectin serine protease 1 Protein (Entity type)	IC50
Mannan-binding lectin serine protease 1 Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:P48740-1 CUI Isoform (Entity type)
(S)-2-((S)-1-((2S,3S)-2-((R)-2-((S)-2-((S)-1-((S)-1-((2S,5S,8S,11S,14R,17S)-20-amino-8-(3-guanidinopropyl)-2,17-bis(4-hydroxybenzyl)-5,11-bis(hydroxymethyl)-14-(mercaptomethyl)-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazaicosane)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-3-methylbutanamido)-3-mercaptopropanamido)-3-methylpentanoyl)pyrrolidine-2-carboxamido)succinic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mannan-binding lectin serine protease 1 Protein (Entity type)	IC50

(2S,5S,8R,11S,14S,17S,20S,23R,26S,29S,32S,35S,41S,44S,50R,53S,56R,59S,62S,65R,68S,71S)-62-(2-amino-2-oxoethyl)-71-((6S,9S,12S,15S)-1-((S)-1-((S)-2-((R)-2-((2S,3R)-2-((S)-2-amino-3-methylbutanamido)-3-hydroxybutanamido)-3-mercaptopropanamido)-4-carboxybutanoyl)pyrrolidin-2-yl)-15-(4-aminobutyl)-12-benzyl-6,9-bis((R)-1-hydroxyethyl)-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecanamido)-2-(3-amino-3-oxopropyl)-14,35,68-tris(4-aminobutyl)-26-benzyl-41-(carboxymethyl)-17,53-bis(3-guanidinopropyl)-5-(4-hydroxybenzyl)-20,59-bis((R)-1-hydroxyethyl)-32,44-bis(hydroxymethyl)-11-isobutyl-8,23,50,56,65-pentakis(mercaptomethyl)-29-methyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70-tricosaoxo-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-tricosaazatriheptacontane-1,73-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mannan-binding lectin serine protease 1
Protein (Entity type)
Ki

(S)-2-((S)-1-((2S,3S)-2-((R)-2-((2S,3S)-2-((S)-1-((S)-1-((2S,5S,8S,11S,14R,17S)-20-amino-17-sec-butyl-8-(3-guanidinopropyl)-5,11-bis(hydroxymethyl)-2-isobutyl-14-(mercaptomethyl)-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazaicosane)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-3-methylpentanamido)-3-mercaptopropanamido)-3-methylpentanoyl)pyrrolidine-2-carboxamido)succinic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mannan-binding lectin serine protease 1
Protein (Entity type)
IC50

Mannan-binding lectin serine protease 1
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:P48740-1 CUI
Isoform (Entity type)

(S)-2-((S)-1-((2S,3S)-2-((R)-2-((S)-2-((S)-1-((S)-1-((2S,5S,8S,11S,14R,17S)-20-amino-8-(3-guanidinopropyl)-2,17-bis(4-hydroxybenzyl)-5,11-bis(hydroxymethyl)-14-(mercaptomethyl)-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazaicosane)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-3-methylbutanamido)-3-mercaptopropanamido)-3-methylpentanoyl)pyrrolidine-2-carboxamido)succinic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mannan-binding lectin serine protease 1
Protein (Entity type)
IC50

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