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Pyruvate kinase PKM (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Pyruvate kinase PKM 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	2-Nitro-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	AC50
	3-(4-(2,6-difluoro-4-methoxyphenylsulfonyl)piperazin-1-ylsulfonyl)aniline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	AC50
	1-(2,6-difluoro-4-methoxyphenylsulfonyl)-4-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	AC50
	2-Methylthio-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	AC50
	Pyruvate kinase PKM Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:P14618-1 CUI Isoform (Entity type)
	Fructose 1-6-bisphosphate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	AC50
	4-(2,3-Dichlorobenzoyl)-N-[[[4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carbonyl]amino]methyl]-1-methyl-pyrrole-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	AC50
	N-(cyclobutylmethyl)-N-(2-fluoro-4-hydroxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	AC50
	6-chloro-N-(3-methoxyphenyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	EC50
	4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazin-1-ylsulfonyl)benzonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pyruvate kinase PKM Protein (Entity type)	AC50

2-Nitro-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
AC50

3-(4-(2,6-difluoro-4-methoxyphenylsulfonyl)piperazin-1-ylsulfonyl)aniline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
AC50

1-(2,6-difluoro-4-methoxyphenylsulfonyl)-4-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
AC50

2-Methylthio-4-methyl-6-[(2-fluorophenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
AC50

Pyruvate kinase PKM
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:P14618-1 CUI
Isoform (Entity type)

Fructose 1-6-bisphosphate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
AC50

4-(2,3-Dichlorobenzoyl)-N-[[[4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carbonyl]amino]methyl]-1-methyl-pyrrole-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
AC50

N-(cyclobutylmethyl)-N-(2-fluoro-4-hydroxybenzyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
AC50

6-chloro-N-(3-methoxyphenyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
EC50

4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazin-1-ylsulfonyl)benzonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pyruvate kinase PKM
Protein (Entity type)
AC50

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