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Somatostatin receptor type 3 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Somatostatin receptor type 3 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(2-(3-(benzo[d][1,3]dioxol-5-yl)-2-methylpropyl)decahydroisoquinolin-4-yl)(4-(5-chloropyridin-2-yl)piperazin-1-yl)methanone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	Kd
	5-((1R,3R)-1-(1-ethyl-1H-pyrazol-4-yl)-3-(4-(5-fluoropyridin-2-yl)-1H-imidazol-2-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1,3,4-oxadiazol-2-ol Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	IC50
	dimethyl 5-((R)-2-methyl-3-((4S,4aS,8aR)-4-(4-(4-nitrophenyl)piperazine-1-carbonyl)octahydroisoquinolin-2(1H)-yl)propyl)isophthalate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	Kd
	N-(4-fluorobenzyl)-1-(4-p-tolyl-1H-imidazol-2-yl)cyclopentanamine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	Ki
	(5S)-6-(benzylamino)-5-((4R)-4-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-ylcarboxamido)-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-6-oxohexan-1-aminium trifluoroacetate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	IC50
	2-(4-{[(2-{2-[2-(2-{[(1R)-1-{[(4R,7S,10S,13R,16S,19S)-10-(4-aminobutyl)-4-{[(1S)-1-carbamoyl-2-(naphthalen-2-yl)ethyl]carbamoyl}-16-{[4-(carbamoylamino)phenyl]methyl}-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2-(4-chlorophenyl)ethyl]carbamoyl}ethoxy)ethoxy]ethoxy}ethyl)carbamoyl]methyl}-7,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	IC50
	N-[(R)-2-(1H-Indol-3-yl)-1-(4-phenyl-1H-imidazol-2-yl)-ethyl]-4-methoxy-benzamidine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	Ki
	N-((1H-indol-3-yl)methyl)-1-(4-(4-fluorophenyl)-1H-imidazol-2-yl)cyclopentanamine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	Ki
	US8754099, 3 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	IC50
	N-((1R,2S)-2-(3,4-dichlorobenzylamino)cyclohexyl)-4-fluorobenzamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 3 Protein (Entity type)	EC50

(2-(3-(benzo[d][1,3]dioxol-5-yl)-2-methylpropyl)decahydroisoquinolin-4-yl)(4-(5-chloropyridin-2-yl)piperazin-1-yl)methanone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
Kd

5-((1R,3R)-1-(1-ethyl-1H-pyrazol-4-yl)-3-(4-(5-fluoropyridin-2-yl)-1H-imidazol-2-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1,3,4-oxadiazol-2-ol
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
IC50

dimethyl 5-((R)-2-methyl-3-((4S,4aS,8aR)-4-(4-(4-nitrophenyl)piperazine-1-carbonyl)octahydroisoquinolin-2(1H)-yl)propyl)isophthalate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
Kd

N-(4-fluorobenzyl)-1-(4-p-tolyl-1H-imidazol-2-yl)cyclopentanamine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
Ki

(5S)-6-(benzylamino)-5-((4R)-4-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-ylcarboxamido)-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-6-oxohexan-1-aminium trifluoroacetate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
IC50

2-(4-{[(2-{2-[2-(2-{[(1R)-1-{[(4R,7S,10S,13R,16S,19S)-10-(4-aminobutyl)-4-{[(1S)-1-carbamoyl-2-(naphthalen-2-yl)ethyl]carbamoyl}-16-{[4-(carbamoylamino)phenyl]methyl}-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2-(4-chlorophenyl)ethyl]carbamoyl}ethoxy)ethoxy]ethoxy}ethyl)carbamoyl]methyl}-7,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
IC50

N-[(R)-2-(1H-Indol-3-yl)-1-(4-phenyl-1H-imidazol-2-yl)-ethyl]-4-methoxy-benzamidine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
Ki

N-((1H-indol-3-yl)methyl)-1-(4-(4-fluorophenyl)-1H-imidazol-2-yl)cyclopentanamine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
Ki

US8754099, 3
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
IC50

N-((1R,2S)-2-(3,4-dichlorobenzylamino)cyclohexyl)-4-fluorobenzamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 3
Protein (Entity type)
EC50

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