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Somatostatin receptor type 2 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Somatostatin receptor type 2 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	US8952128, 39 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	Ki
	US8952128, 12::US8952128, 46 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	Ki
	Somatostatin analogue Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	IC50
	(S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(thiophene-2-sulfonyl)-piperidine-3-carbonyl]-amino}-butyrylamino)-hexanoic acid tert-butyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	Ki
	2-amino-N-[(7R,10S,13R,16R,19R,22S)-13-(4-aminobutyl)-7,22-dibenzyl-5-(carbamoylmethyl)-10-[(1R)-1-hydroxyethyl]-16,19-bis(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaazacyclohexacosan-25-yl]-3-phenylpropanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	IC50
	US8952128, 29A Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	Ki
	US8952128, 26 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	Ki
	2,2',2''-(10-((S)-6-((4R,7S,10S,13S,16S,19R,22S,25S,28R)-19-((1H-indol-3-yl)methyl)-16-(4-aminobutyl)-10,22,25-tribenzyl-4-carboxy-13-((R)-1-hydroxyethyl)-7-(hydroxymethyl)-6,9,12,15,18,21,24,27-octaoxo-1,2-dithia-5,8,11,14,17,20,23,26-octaazacyclononacosan-28-ylcarbamoyl)-1-amino-1-imino-8,17-dioxo-10,13-dioxa-2,7,16-triazaoctadecan-18-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	IC50
	(R)-7-chloro-3-(3,5-dimethylphenyl)-4-(2-(piperidin-2-yl)ethoxy)-N-(pyrimidin-4-yl)quinoline-6-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	Ki
	US8952128, 24 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Somatostatin receptor type 2 Protein (Entity type)	Ki

US8952128, 39
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
Ki

US8952128, 12::US8952128, 46
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
Ki

Somatostatin analogue
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
IC50

(S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(thiophene-2-sulfonyl)-piperidine-3-carbonyl]-amino}-butyrylamino)-hexanoic acid tert-butyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
Ki

2-amino-N-[(7R,10S,13R,16R,19R,22S)-13-(4-aminobutyl)-7,22-dibenzyl-5-(carbamoylmethyl)-10-[(1R)-1-hydroxyethyl]-16,19-bis(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaazacyclohexacosan-25-yl]-3-phenylpropanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
IC50

US8952128, 29A
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
Ki

US8952128, 26
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
Ki

2,2',2''-(10-((S)-6-((4R,7S,10S,13S,16S,19R,22S,25S,28R)-19-((1H-indol-3-yl)methyl)-16-(4-aminobutyl)-10,22,25-tribenzyl-4-carboxy-13-((R)-1-hydroxyethyl)-7-(hydroxymethyl)-6,9,12,15,18,21,24,27-octaoxo-1,2-dithia-5,8,11,14,17,20,23,26-octaazacyclononacosan-28-ylcarbamoyl)-1-amino-1-imino-8,17-dioxo-10,13-dioxa-2,7,16-triazaoctadecan-18-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
IC50

(R)-7-chloro-3-(3,5-dimethylphenyl)-4-(2-(piperidin-2-yl)ethoxy)-N-(pyrimidin-4-yl)quinoline-6-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
Ki

US8952128, 24
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Somatostatin receptor type 2
Protein (Entity type)
Ki

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