Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H 's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(2S)-1-cyclohexylpropan-2-yl 1-cyanopyrrolidine-2-carboxylate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	IC50
9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	IC50
{(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid (S)-1-methyl-2-phenyl-ethyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	IC50
((S)-1-Formyl-pentyl)-carbamic acid (S)-1-methyl-2-phenyl-ethyl ester Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	IC50
compound 1e [PMID: 27285276] Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	IC50
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:P09668-1 CUI Isoform (Entity type)
(R)-3-methyl-1-phenylbutan-2-yl (S)-1-oxohexan-2-ylcarbamate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	IC50
6-(3,5-Difluorophenylamino)-9-ethyl-9H-purine-2-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	IC50
(2S)-1-cyclohexylpropan-2-yl 1-cyanoazetidine-2-carboxylate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	IC50
(1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-isopropylhydrazinecarboxylate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H Protein (Entity type)	Ki

(2S)-1-cyclohexylpropan-2-yl 1-cyanopyrrolidine-2-carboxylate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
IC50

9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-carbonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
IC50

{(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid (S)-1-methyl-2-phenyl-ethyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
IC50

((S)-1-Formyl-pentyl)-carbamic acid (S)-1-methyl-2-phenyl-ethyl ester
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
IC50

compound 1e [PMID: 27285276]
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
IC50

Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:P09668-1 CUI
Isoform (Entity type)

(R)-3-methyl-1-phenylbutan-2-yl (S)-1-oxohexan-2-ylcarbamate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
IC50

6-(3,5-Difluorophenylamino)-9-ethyl-9H-purine-2-carbonitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
IC50

(2S)-1-cyclohexylpropan-2-yl 1-cyanoazetidine-2-carboxylate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
IC50

(1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-isopropylhydrazinecarboxylate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H
Protein (Entity type)
Ki

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