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Serine/threonine-protein kinase PAK 6 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Serine/threonine-protein kinase PAK 6 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Staurosporine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PAK 6 Protein (Entity type)	Kd
	UCN-01 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PAK 6 Protein (Entity type)	Kd
	GSK-690693 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PAK 6 Protein (Entity type)	IC50
	compound 4 [PMID: 24432870] Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PAK 6 Protein (Entity type)	IC50
	PUBCHEM:155552127 CUI Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PAK 6 Protein (Entity type)	Kd
	16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaen-3-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PAK 6 Protein (Entity type)	Kd
	[3-{2-[(3,5-Dimethyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}-N-(2-{2-[2-(2-{[(5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]amino}ethoxy)ethoxy]ethoxy}ethyl)propanamidato](difluoro)borone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PAK 6 Protein (Entity type)	Kd
	PF-3758309 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PAK 6 Protein (Entity type)	IC50

Staurosporine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PAK 6
Protein (Entity type)
Kd

UCN-01
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PAK 6
Protein (Entity type)
Kd

GSK-690693
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PAK 6
Protein (Entity type)
IC50

compound 4 [PMID: 24432870]
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PAK 6
Protein (Entity type)
IC50

PUBCHEM:155552127 CUI
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PAK 6
Protein (Entity type)
Kd

16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaen-3-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PAK 6
Protein (Entity type)
Kd

[3-{2-[(3,5-Dimethyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}-N-(2-{2-[2-(2-{[(5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]amino}ethoxy)ethoxy]ethoxy}ethyl)propanamidato](difluoro)borone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PAK 6
Protein (Entity type)
Kd

PF-3758309
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PAK 6
Protein (Entity type)
IC50

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