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Purine nucleoside phosphorylase (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Purine nucleoside phosphorylase 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	2-amino-1,5-dihydro-7-[[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]methyl]-4H-pyrrolo[3,2-d]pyrimidin-4-one diacetate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki
	[3,3-Dimethyl-5-(6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-phosphonic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki
	2,6-diamino-7-(thiophen-3-ylmethyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki
	4-(2-amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)-1,1-difluorobutylphosphonic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	IC50
	7-(3,4-Dihydroxy-5-methyl-pyrrolidin-2-yl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki
	7-({[(2S)-2,3-Dihydroxypropyl](2-hydroxyethyl)amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki
	7-(4-Hydroxy-5-hydroxymethyl-pyrrolidin-2-yl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki
	[6-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-hexyl]-phosphonic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki
	[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-pentyl]-phosphonic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki
	[8-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-octyl]-phosphonic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Purine nucleoside phosphorylase Protein (Entity type)	Ki

2-amino-1,5-dihydro-7-[[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]methyl]-4H-pyrrolo[3,2-d]pyrimidin-4-one diacetate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

[3,3-Dimethyl-5-(6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-phosphonic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

2,6-diamino-7-(thiophen-3-ylmethyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

4-(2-amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)-1,1-difluorobutylphosphonic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
IC50

7-(3,4-Dihydroxy-5-methyl-pyrrolidin-2-yl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

7-({[(2S)-2,3-Dihydroxypropyl](2-hydroxyethyl)amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

7-(4-Hydroxy-5-hydroxymethyl-pyrrolidin-2-yl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

[6-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-hexyl]-phosphonic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-pentyl]-phosphonic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

[8-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-octyl]-phosphonic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Purine nucleoside phosphorylase
Protein (Entity type)
Ki

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025