Oxytocin receptor (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Oxytocin receptor 's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
[<sup>35</sup>S]non-peptide OT antagonist Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	Kd
(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-sec-butyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((S)-1-(2-amino-2-oxoethylamino)-1-oxooctan-2-yl)pyrrolidine-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	EC50
(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-6-isobutyl-1-((R)-1-(2-methyloxazol-4-yl)-2-morpholino-2-oxoethyl)piperazine-2,5-dione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	Ki
c(Cys-Tyr-Ile-Gln-Asn-Cys)-(S)-2-(methoxymethyl)pyrrolidine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	EC50
2-Methoxy-5-[3-(2'-methoxy-biphenyl-4-yl)-5-methoxymethyl-[1,2,4]triazol-4-yl]-pyridine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	Ki
1-(1-{2-Methoxy-4-[1-(2,4,6-trimethyl-1-oxy-pyridin-3-ylmethyl)-piperidin-4-yloxy]-benzoyl}-piperidin-4-yl)-1,4-dihydro-benzo[d][1,3]oxazin-2-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	Ki
(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-sec-butyl-20,20-diethyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((S)-1-(2-amino-2-oxoethylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	Kd
N-(3-chloro-2-methylphenyl)-2-(N-(4-methoxyphenyl)phenylsulfonamido)acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	Ki
(S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tolylpiperazin-1-ylsulfonyl)methyl)bicyclo[2.2.1]heptan-2-yl)-4-(methylsulfonyl)butanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	Ki
4-chloro-N-(1-(pyridin-2-yl)-1H-pyrazol-5-yl)benzenesulfonamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Oxytocin receptor Protein (Entity type)	EC50

[<sup>35</sup>S]non-peptide OT antagonist
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
Kd

(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-sec-butyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((S)-1-(2-amino-2-oxoethylamino)-1-oxooctan-2-yl)pyrrolidine-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
EC50

(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-6-isobutyl-1-((R)-1-(2-methyloxazol-4-yl)-2-morpholino-2-oxoethyl)piperazine-2,5-dione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
Ki

c(Cys-Tyr-Ile-Gln-Asn-Cys)-(S)-2-(methoxymethyl)pyrrolidine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
EC50

2-Methoxy-5-[3-(2'-methoxy-biphenyl-4-yl)-5-methoxymethyl-[1,2,4]triazol-4-yl]-pyridine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
Ki

1-(1-{2-Methoxy-4-[1-(2,4,6-trimethyl-1-oxy-pyridin-3-ylmethyl)-piperidin-4-yloxy]-benzoyl}-piperidin-4-yl)-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
Ki

(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-sec-butyl-20,20-diethyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((S)-1-(2-amino-2-oxoethylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
Kd

N-(3-chloro-2-methylphenyl)-2-(N-(4-methoxyphenyl)phenylsulfonamido)acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
Ki

(S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tolylpiperazin-1-ylsulfonyl)methyl)bicyclo[2.2.1]heptan-2-yl)-4-(methylsulfonyl)butanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
Ki

4-chloro-N-(1-(pyridin-2-yl)-1H-pyrazol-5-yl)benzenesulfonamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Oxytocin receptor
Protein (Entity type)
EC50

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