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Lysosomal acid glucosylceramidase (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Lysosomal acid glucosylceramidase 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	4-methyl-N-(4-methyl-2-(4-methylpiperidin-1-yl)quinolin-6-yl)cyclohexanecarboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	Ki
	N-(2,3-Dihydro-1H-inden-1-yl)-2-(pyridin-3-yl)quinazolin-4-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	IC50
	(2R,3S,4S,5R)-3,4,5-Trihydroxy-2-(2-octylsulfanyl-ethyl)-piperidine hydrochloride Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	Ki
	(S)-N-methyl-2-(pyridin-3-yl)-N-(1,2,3,4-tetrahydronaphthalen-2-yl)quinazolin-4-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	IC50
	(cis/trans)-N-(4-Ethylcyclohexyl)-2-(pyridin-3-yl)quinazolin-4-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	IC50
	N-(2-Cyclohexylethyl)-2-(pyridin-3-yl)quinazolin-4-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	IC50
	N-nonyloxypentyl D-deoxynojirimycin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	IC50
	(2R,3S,4S,5R)-2-[2-(N-benzyl-2-acetamidyl)sulfanyl-ethyl]-3,4,5-trihydroxy-piperidine hydrochloride Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	Ki
	N-[5-((4'-fluoro[1,1'-biphenyl]-4-yl)-methoxy)-pentyl]-1-deoxynojirimycin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	IC50
	US9119845, 24 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Lysosomal acid glucosylceramidase Protein (Entity type)	Ki

4-methyl-N-(4-methyl-2-(4-methylpiperidin-1-yl)quinolin-6-yl)cyclohexanecarboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
Ki

N-(2,3-Dihydro-1H-inden-1-yl)-2-(pyridin-3-yl)quinazolin-4-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
IC50

(2R,3S,4S,5R)-3,4,5-Trihydroxy-2-(2-octylsulfanyl-ethyl)-piperidine hydrochloride
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
Ki

(S)-N-methyl-2-(pyridin-3-yl)-N-(1,2,3,4-tetrahydronaphthalen-2-yl)quinazolin-4-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
IC50

(cis/trans)-N-(4-Ethylcyclohexyl)-2-(pyridin-3-yl)quinazolin-4-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
IC50

N-(2-Cyclohexylethyl)-2-(pyridin-3-yl)quinazolin-4-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
IC50

N-nonyloxypentyl D-deoxynojirimycin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
IC50

(2R,3S,4S,5R)-2-[2-(N-benzyl-2-acetamidyl)sulfanyl-ethyl]-3,4,5-trihydroxy-piperidine hydrochloride
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
Ki

N-[5-((4'-fluoro[1,1'-biphenyl]-4-yl)-methoxy)-pentyl]-1-deoxynojirimycin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
IC50

US9119845, 24
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Lysosomal acid glucosylceramidase
Protein (Entity type)
Ki

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