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3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-oxo-5-alpha-steroid 4-dehydrogenase 2 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(1S,3aS,3bS,9aR,9bS,11aS)-6-chloro-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	IC50
	17a-(2-Propionoxyethyl)-17-oxo-17a-aza-D-homo-3,5-androstadien-3-oic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	IC50
	6-Benzyloxy-5-methoxy-1H-indole-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	Ki
	(1S,3aS,3bS,9aR,9bS,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylicacid adamantan-2-ylamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	IC50
	4'-[(Diisopropylcarbamoyl)-methoxy]-2-trifluoromethyl-biphenyl-4-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	IC50
	4-(1-Diphenylcarbamoyl-piperidin-4-ylidenemethyl)-benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	IC50
	2-((4aR,10bR)-4,10b-Dimethyl-3-oxo-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-8-yl)-N-phenyl-acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	IC50
	4-(4-Phenylacetyl-benzoyl)-benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	Ki
	(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-chloro-phenyl)-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	IC50
	(1S,3aS,3bS,9aR,9bS,11aS)-N,N-diethyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 Protein (Entity type)	IC50

(1S,3aS,3bS,9aR,9bS,11aS)-6-chloro-N,N-diethyl-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
IC50

17a-(2-Propionoxyethyl)-17-oxo-17a-aza-D-homo-3,5-androstadien-3-oic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
IC50

6-Benzyloxy-5-methoxy-1H-indole-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
Ki

(1S,3aS,3bS,9aR,9bS,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxylicacid adamantan-2-ylamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
IC50

4'-[(Diisopropylcarbamoyl)-methoxy]-2-trifluoromethyl-biphenyl-4-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
IC50

4-(1-Diphenylcarbamoyl-piperidin-4-ylidenemethyl)-benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
IC50

2-((4aR,10bR)-4,10b-Dimethyl-3-oxo-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-8-yl)-N-phenyl-acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
IC50

4-(4-Phenylacetyl-benzoyl)-benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
Ki

(4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid (3-chloro-phenyl)-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
IC50

(1S,3aS,3bS,9aR,9bS,11aS)-N,N-diethyl-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein (Entity type)
IC50

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