Frizzled-7 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Frizzled-7 's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-1-oxo-3-p-tolylpropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-diisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd
(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,15,32,38-tetraisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd
(3S,6S,9S,12S,15S,18S,21R,27S,30S,33S,36S,39S,42S,45S)-18,30-bis((1H-indol-3-yl)methyl)-45-((2S,3R)-2-acetamido-3-hydroxybutanamido)-3-((2S,3S)-2-acetamido-3-hydroxybutanamido)-21,27-bis((S)-1-((2S,3S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxopentan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-12,36-bis(2-carboxyethyl)-6,42-bis(carboxymethyl)-9,15,33,39-tetraisobutyl-4,7,10,13,16,19,29,32,35,38,41,44-dodecaoxo-23,24-dithia-5,8,11,14,17,20,28,31,34,37,40,43-dodecaazaheptatetracontane-1,47-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd
(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((R)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-4,4-dimethyl-1-oxopentan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-diisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd
(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-12,35-bis(4-aminobutyl)-6,41-bis(carboxymethyl)-9,15,32,38-tetraisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd
(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((R)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-cyclopentyl-1-oxopropan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-diisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd
Frizzled-7 Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:O75084-1 CUI Isoform (Entity type)
(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((2S,3R)-2-acetamido-3-hydroxybutanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-diisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd
(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-bis(cyclopentylmethyl)-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd
(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-9,38-dibutyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Frizzled-7 Protein (Entity type)	Kd

(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-1-oxo-3-p-tolylpropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-diisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,15,32,38-tetraisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

(3S,6S,9S,12S,15S,18S,21R,27S,30S,33S,36S,39S,42S,45S)-18,30-bis((1H-indol-3-yl)methyl)-45-((2S,3R)-2-acetamido-3-hydroxybutanamido)-3-((2S,3S)-2-acetamido-3-hydroxybutanamido)-21,27-bis((S)-1-((2S,3S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxopentan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-12,36-bis(2-carboxyethyl)-6,42-bis(carboxymethyl)-9,15,33,39-tetraisobutyl-4,7,10,13,16,19,29,32,35,38,41,44-dodecaoxo-23,24-dithia-5,8,11,14,17,20,28,31,34,37,40,43-dodecaazaheptatetracontane-1,47-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((R)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-4,4-dimethyl-1-oxopentan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-diisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-12,35-bis(4-aminobutyl)-6,41-bis(carboxymethyl)-9,15,32,38-tetraisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((R)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-cyclopentyl-1-oxopropan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-diisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

Frizzled-7
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:O75084-1 CUI
Isoform (Entity type)

(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((2S,3R)-2-acetamido-3-hydroxybutanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-diisobutyl-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-9,38-bis(cyclopentylmethyl)-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

(3S,6S,9S,12S,15S,18S,21R,26R,29S,32S,35S,38S,41S,44S)-18,29-bis((1H-indol-3-yl)methyl)-3,44-bis((S)-2-acetamido-3-hydroxypropanamido)-21,26-bis((S)-1-((S)-1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-4-(methylthio)-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylcarbamoyl)-15,32-dibenzyl-9,38-dibutyl-12,35-bis(2-carboxyethyl)-6,41-bis(carboxymethyl)-4,7,10,13,16,19,28,31,34,37,40,43-dodecaoxo-23,24-dithia-5,8,11,14,17,20,27,30,33,36,39,42-dodecaazahexatetracontane-1,46-dioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Frizzled-7
Protein (Entity type)
Kd

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